The publications contained in this archive section are provided for historical purposes only. The views expressed in the publications are those of their respective authors and do not reflect the views of NOXXON. NOXXON disavows any obligation to update or correct the information contained in these publications.

Wang J, Benedetti E, Bethge L, Vonhoff S, Klussmann S, Vasseur JJ, Cossy J, Smietana M, Arseniyadis S.
DNA vs. mirror image DNA: A universal approach to tune the absolute configuration in DNA-based asymmetric catalysis.

Angew. Chem. Int. Ed. Engl.
2013, 52(40), 11546-9.
view PubMed abstract on ncbi.nlm.nih.gov

Achenbach J, Nierhaus KH.
Translocation at work.

Nat Struct Mol Biol.
2013, 20(9), 1019-22.
view abstract on nature.com

Hoehlig K, Maasch C, Shushakova N, Buchner K, Huber-Lang M, Purschke WG, Vater A, Klussmann S.
A Novel C5a-neutralizing Mirror-image (L-)Aptamer Prevents Organ Failure and Improves Survival in Experimental Sepsis
.
Mol Ther.
2013, 21(12):2236-46.
read article on nature.com

Vater A, Sell S, Kaczmarek P, Maasch C, Buchner K, Pruszynska-Oszmalek E, Kolodziejski P, Purschke WG, Nowak KW, Strowski MZ, Klussmann S.
A Mixed Mirror-image DNA/RNA Aptamer Inhibits Glucagon and Acutely Improves Glucose Tolerance in Models of Type 1 and Type 2 Diabetes
.
J Biol Chem.
2013, Vol 288(29), 21136-47.
read article on jbc.org

Schneider G, Bryndza E, Abdel-Latif A, Ratajczak J, Maj M, Tarnowski M, Klyachkin Y, Houghton P, Morris AJ, Vater A, Klussmann S, Kucia M, Ratajczak MZ.
Bioactive lipids S1P and C1P are pro-metastatic factors in human rhabdomyosarcomas cell lines, and their tissue level increases in response to radio/chemotherapy.

Mol Cancer Res.
2013, 11(7), 793-807.
view PubMed abstract on ncbi.nlm.nih.gov

Vater A, Sahlmann J, Kröger N, Zöllner S, Lioznov M, Maasch C, Buchner K, Vossmeyer D, Schwoebel F, Purschke WG, Vonhoff S, Kruschinski A, Hübel K, Humphrey M, Klussmann S, Fliegert F.
Hematopoietic stem and progenitor cell mobilization in mouse and man by a first-in-class mirror-image oligonucleotide inhibitor of CXCL12.

Clinical Pharmacology and Therapeutics.
2013, 94(1), 150-7.
read article on wiley.com

Khan MA, Maasch C, Vater A, Klussmann S, Morser J, Leung LL, Atkinson C, Tomlinson S, Heeger PS, Nicolls MR.
Targeting complement component 5a promotes vascular integrity and limits airway remodeling.

PNAS.
2013, 110(15), 6061-6.
read article on pnas.org

Schwoebel F, van Eijk LT, Zboralski D, Sell S, Buchner K, Maasch C, Purschke WG, Humphrey M, Zöllner S, Eulberg D, Morich F, Pickkers P, Klussmann S.
The effects of the anti-hepcidin Spiegelmer NOX-H94 on inflammation-induced anemia in cynomolgus monkeys.

Blood.
2013, Vol 121(12), 2311-15.
read article on bloodjournal.hematologylibrary.org