The publications contained in this archive section are provided for historical purposes only. The views expressed in the publications are those of their respective authors and do not reflect the views of NOXXON. NOXXON disavows any obligation to update or correct the information contained in these publications.

Riecke K, Ludwig H, van Eijk L, Boyce M, Pickkers P, Macdougall I, Schwöbel F, Swinkels D.
Clinical Pharmacology, Efficacy, and Safety of the Anti-Hepcidin Spiegelmer Lexaptepid Pegol (NOX-H94).

European Iron Club
2014, Verona
Presentation

Georgiev P, Lazaroiu M, Ocroteala L, Grudeva-Popova J, Gheorghita E, Vasilica M, Popescu S, Cucuianu A, Summo L, Schwoebel F, Riecke K, Ludwig H.
The Anti-Hepcidin Spiegelmer Lexaptepid Pegol (NOX-H94) as Treatment of Anemia of Chronic Disease in Patients with Multiple Myeloma, Low Grade Lymphoma, and CLL: a Phase II pilot Study.

European Hematology Association
2014, Milan
Poster

Georgiev P, Lazaroiu M, Ocroteala L, Grudeva-Popova J, Gheorghita E, Vasilica M, Popescu SM, Cucuianu A, Summo L, Schwoebel F, Riecke K, Ludwig H.
The anti-hepcidin Spiegelmer Lexaptepid Pegol (NOX-H94) as treatment of anemia of chronic disease in patients with multiple myeloma, low grade lymphoma, and CLL: A phase II pilot study.
Cancer Research. 2014, 74, 3847.
read abstract on aacrjournals.org

van Eijk LT, John AS, Schwoebel F, Summo L, Vauléon S, Zöllner S, Laarakkers CM, Kox M, van der Hoeven JG, Swinkels DW, Riecke K, Pickkers P.
Effect of the antihepcidin Spiegelmer lexaptepid on inflammation-induced decrease in serum iron in humans.
Blood. 2014, 124(17), 2643-6.
read article on bloodjournal.org

Steinbicker AU.
Comment on van Eijk et al
A novel treatment of anemia of inflammation.

Blood.
2014, 124(17), 2618-19.
read comment on bloodjournal.org

Schwoebel F, van Eijk LT, Zboralski D, Sell S, Buchner K, Maasch C, Purschke WG, Humphrey M, Zöllner S, Eulberg D, Morich F, Pickkers P, Klussmann S.
The effects of the anti-hepcidin Spiegelmer NOX-H94 on inflammation-induced anemia in cynomolgus monkeys.
Blood. 2013, Vol 121(12), 2311-15.
read article on bloodjournal.hematologylibrary.org

Riecke K, Zöllner S,Boyce M, Vauléon S, Swinkels DW, Dümmler T, Summo L, Laarakkers C, Schwoebel F, Fliegert F
Single and Repeated Dose First-in-Human Study with the Anti-Hepcidin Spiegelmer NOX-H94.
Blood (ASH Annual Meeting Abstracts) 2012 120: Abstract 2342
read ASH abstract on hematologylibrary.org

van Eijk L, Swinkels DW, Aaron J,Schwoebel F, Fliegert F, Summo L, Vauleon S, Laarakkers C, Riecke K, Pikkers P
Randomized Double Blind Placebo Controlled PK/PD Study On the Effects of a Single Intravenous Dose of the Anti-Hepcidin Spiegelmer NOX-H94 On Serum Iron During Experimental Human Endotoxemia
Blood (ASH Annual Meeting Abstracts) 2012 120: Abstract 3452
read ASH abstract on hematologylibrary.org