The publications contained in this archive section are provided for historical purposes only. The views expressed in the publications are those of their respective authors and do not reflect the views of NOXXON. NOXXON disavows any obligation to update or correct the information contained in these publications.

Maasch, C., Buchner, K., Eulberg, D., Vonhoff, S. & Klussmann, S.
Physicochemical stability of NOX-E36, a 40mer L‑RNA (Spiegelmer) for therapeutic applications.
Nucleic Acids Symp.Ser. 2008, No. 52, 61-62.
view PubMed abstract on ncbi.nlm.nih.gov

Deng, X., Klussmann, S., Wu, G.-M., Akkerman, D., Zhu, Y.-Q., Liu, Y., Chen, H., Zhu, P., Yu, B.-Z. & Zhang, G.-L.
Effect of LHRH-PE40 on target cells via LHRH receptors.
J. Drugetg Tar. 2008, Vol. 16(5), 379-388.
view PubMed abstract on ncbi.nlm.nih.gov

Schlesinger, J., Koezle, I., Bergmann, R., Tamburini, S., Bolzati, C., Tisato, F., Noll, B., Klussmann, S., Vonhoff, S., Wuest, F., Pietsch, H. J. & Steinbach, J.
An 86Y-labeled mirror-image oligonucleotide: influence of Y-DOTA isomers on the biodistribution in rats.
Bioconjug. Chem. 2008, Vol. 19(4), 928-939.
view PubMed abstract on ncbi.nlm.nih.gov

Ninichuk, V., Clauss, S., Kulkarni, O., Schmid, H., Segerer, S., Radomska, E., Eulberg, D., Buchner, K., Selve, N., Klussmann, S., & Anders, H.-J.
Late onset of Ccl2 blockade with the Spiegelmer mNOX-E36-3'PEG prevents glomerulosclerosis and improves glomerular filtration rate in db/db mice.
Am. J. Pathol. 2008, Vol. 172(3), 628-637.
view PubMed abstract on ncbi.nlm.nih.gov

Becskei C, Bilik KU, Klußmann S, Jarosch F, Lutz TA, Riediger T.
The Anti-Ghrelin Spiegelmer NOX-B11-3 Blocks Ghrelin- but not Fasting-Induced Neuronal Activation in the Hypothalamic Arcuate Nucleus.
J Neuroendocrinol 2008, Vol. 20(1), 85-92.
view PubMed abstract on ncbi.nlm.nih.gov

Eulberg, D., Purschke, W., Anders, H.-J., Selve, N. & Klussmann, S.
Spiegelmer NOX-E36 for Renal Diseases.
Therapeutic Oligonucleotides 2008, Ed. Jens Kurreck, Biomolecular Sciences Series of the Royal Society of Chemistry (RSC).

Bilik, K., Ergüven, E., Klußmann, S., Jarosch, F., Wielinga, P. Y., Lutz, T. A. & Riediger, T.
In vitro and in vivo antagonistic action of an anti-amylin Spiegelmer.
Neuroreport 2007, Vol. 18(17), 1855-1859.
view PubMed abstract on ncbi.nlm.nih.gov

Bolik, S, Rübhausen, M., Binder, S., Schulz, B., Perbandt, M., Genov, N., Erdmann, V. A., Klußmann, S., & Betzel, C.
First experimental evidence for the preferential stabilization of the natural D- over the nonnatural L-configuration in nucleic acids.
RNA 2007, Vol. 13(11), 1877-1880
view PubMed abstract on ncbi.nlm.nih.gov

Kulkarni, O., Pawar, R. D., Purschke, W., Eulberg, D., Selve, N., Buchner, K., Ninichuk, V., Segerer, S., Vielhauer, V., Klußmann, S., & Anders, H.-J.
Spiegelmer inhibition of CCL2/MCP-1 ameliorates lupus nephritis in MRL-(Fas)lpr mice.
J. Am. Soc. Nephrol. 2007, Vol. 18, 2350-2358.
view PubMed abstract on ncbi.nlm.nih.gov

Lai, J. C., Brown, B. D., Voskresenskiy, A M., Vonhoff, S., Klußmann, S., Tan, W., Colombini, M., Weeratna, R., Miller, P., Benimetskaya, L. & Stein, C. A.
Comparsion of D-g3139 and ist enantiomer L-g3139 in melanoma cells demonstrates minimal in vitro but dramtic in vivo chiral dependency.
Mol. Ther. 2007, Vol. 15(2), 270-278.
view PubMed abstract on ncbi.nlm.nih.gov